Metis ReGenesis: Decentralized AI on the Blockchain

Layer 2 blockchain Metis is taking an ambitious step into the future by launching the ReGenesis initiative, which connects artificial intelligence (AI) with decentralized finance (DeFi) on Ethereum. This system, announced at the beginning of 2025, integrates AI, proof mechanisms, liquidity, and autonomous agents at the L2 level, making it a hot topic in the DeFi+AI community. Metis co-founder Elena Sinelnikova in an interview for TheStreet emphasized the focus on data ownership in AI, positioning ReGenesis as a solution to the problems of centralized giants like Google. The mainnet launch took place on November 11, 2025, and has already attracted attention due to integration with LazAI and the AI agent Alith.

How Does Metis ReGenesis Work?

ReGenesis is not just an upgrade, but a complete transformation of Metis into an ecosystem where AI and blockchain function as a single entity. Key components include:

• A new virtual machine that enhances scalability, speed, and reduces gas costs, ideal for AI applications, gaming, and DeFi. This addresses the issues of slow growth in Ethereum L2, making the network ready for the "AI + Web3" era.
• A platform for decentralized AI, where data is tokenized through DAT (Data Anchored Tokens) and managed by iDAO (intelligent DAO). This ensures verification of AI content, models, and results using "Verified Computing." LazAI allows users to own their data, turning it into tradable assets.
• An autonomous agent that automates DeFi strategies, monitors airdrops, arbitrage opportunities, and analyzes data/NFTs. Alith acts as a "24/7 AI assistant" for on-chain operations, integrating AI models into a unified network.

The initiative also includes decentralized sequencers, chain-off data availability (DA) for cost reduction, and full compatibility with Ethereum. The full launch is expected at ETHDenver, with gradual rollout of components.

How ReGenesis Solves Problems of Centralized AI?

Centralized AI systems, like those from Google or OpenAI, control user data, leading to issues with privacy, training biases, and lack of ownership. ReGenesis offers a decentralized alternative:

1. Users tokenize their datasets through LazAI, receiving a share of the economic growth from AI. This counters models where data is monopolized by corporations.
2. Verified Computing ensures transparency of AI results on the blockchain, reducing biases and making AI accessible on an open network.
3. DeFAI (DeFi + AI) automates liquidity pools, DAO voting, and assets, making Web3 more efficient.

Elena Sinelnikova in the interview noted: "We are creating systems where users own the data" emphasizing the shift from centralization to decentralized AI infrastructure.

Key to AI+Web3

Metis ReGenesis signals the evolution from a simple L2 to a decentralized AI ecosystem, solving centralization issues and opening new opportunities for data and DeFi. With a focus on LazAI and Alith, this could become the "next big thing" in Web3. For beginners - a chance to start small, but with an understanding of risks.